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The Food and Drug Administration has called cigarettes "the only legal consumer product that, when used as intended, will kill half of all long-term users." But the agency has never regulated nicotine, cigarettes' notoriously addictive ingredient and for years, it has been wanting to change that

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therefore, chemical residues and viable microorganisms on tobacco leaf surfaces may persist during production, and may be present at some level in finished ST products (Wiernik et al

Philip Morris International, the force behind Marlboro, has staked its future on IQOS, a heat-not-burn device designed as an alternative to traditional cigarettes